Posted by Hooke 10/26/2024
(Replying to the comment that you made before completely rewriting it.)
You're completely wrong about the sugar pill (or at least whether or not it matters) - it's one of the issues with psychedelic medicines: there's no viable placebo at higher doses, and it's the higher doses that seem to have the deepest and longest lasting impact on depression.
Most people certainly aren't capable of having the same kind of experience without the substance, goes for all of the ones I mentioned and more.
And while we haven't been able to do the amount of science one could wish for, because of criminalization; there's plenty of experience out there and enough science to understand how the drugs deliver their effect.
Using psychedelics to improve anything (except maybe some forms of art) seems to me like when writers would drink to help them write. There's never going to be any rigorous evidence for any benefit.