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Posted by PaulHoule 5 hours ago

Diesel pollution particles impair lysosomal functions of iPSC-derived microglia(www.sciencedirect.com)
24 points | 14 comments
w10-1 2 hours ago|
The finding is that older diesel engines and renewables produce measurable adverse effects in microglial stem cells, but new diesel formulations in new engines do not. The implication is that policy-makers should accelerate the transition to newer diesel and abandon reusable diesel. Since Europe has been gung-ho for diesel for decades, this finding could have significant regulatory and market effects.
calmbonsai 2 hours ago||
I will never forgive VW for cheating on diesel emissions. That corruption went so far throughout the org the entire company should've been criminally indicted and shut down.
general1465 46 minutes ago||
Compared to what diesel trucks running across the country are exhaling daily, then what VW did is absurdly negligible.
OptionOfT 1 hour ago||
And there was a solution available. AdBlue. Mercedes already used it, and so did BMW. But VW didn't want to use it.

And because of this scandal VW pulled their diesels, AND both Mercedes and BMW followed suit.

Quite sad, because an X5 diesel had really good mileage (if you used it for longer distances).

kyleee 3 hours ago||
Seems intuitive, I have always had a strong negative reaction to inhaling diesel exhaust / particulate matter. Nasty stuff
e-dant 4 hours ago|
It blows my mind that we need any research at all to convince us that shoving tons of burning oil down our throats is a bad thing

Maybe, next time we need to drive 5 miles for groceries, we should just fucking walk, and say hi to one another, too

i80and 4 hours ago||
Very few people want to walk 5 miles for groceries. I'm lucky enough to be able to walk to my grocery store, and even being healthy and able, 1 mile each way is the most I want to do.

Bicycling would make 5 miles a cinch, however.

calmbonsai 2 hours ago||
Not related, cargo bikes absolutely rule if you have a decent climate and suitably safe biking infrastructure.
oblio 1 hour ago||
Even the "decent climate" range is actually huge, <especially with ebikes>. Basically I can think of only a one climate where life on bikes is really hard: very hot and humid.

Hot and dry is manageable since when cycling you naturally create cooling currents around you; you need to wear appropriate clothing (sunglasses + cap or helmet with shaded visor; appropriate long sleeved shirt, appropriate pants and shoes).

https://youtu.be/2opQQP13lPI?si=LdhJnF8yLKrVNuGM (for long sleeved shirts)

Cold climates are super manageable with appropriate clothing, bar mitts and most crucially of all: <well designed bike infrastructure including priority maintenance, just like for car infrastructure>.

https://www.youtube.com/watch?v=Uhx-26GfCBU

Of course super extreme weather like -30C or +40C at some point makes any active transportation close to impossible, but the vast majority of people don't live in those conditions and the people that do live like that, only do it for max 1-2 months per year.

99.99% of these issues are actually failures of infrastructure design and implementation.

For snowy conditions: daily snow plowing, debris removal, salting to prevent ice formation, etc, etc.

For hot conditions: planting trees, removing asphalt (for example grassy tram/train lines; parking spots with grass pavers (https://buildwithabs.com/product/grass-pavers/), designing tall buildings to shade urban sidewalks, etc.

Also, infrastructure doesn't just need to safe, it needs to be maintained as critical infrastructure, just like for cars, so that the infra is not degraded in practice.

D13Fd 3 hours ago|||
5 miles is a long walk. That’s at least 1 hour and 15 minutes for a very fast walker, and probably around 2 hours for a more typical walker.

Plus you have to walk back, with groceries. Assuming you are feeding a family and not doing this 2-4 hour round trip every day, that means you’ll need a cart to push or pull.

Good luck pushing that loaded cart on a road with any amount of traffic. Most places in the U.S. where the grocery store is 5 miles away will involve either zero sidewalks and dangerous roads (more rural/suburban areas), or many many road crossings with lights that slow you down (denser areas).

I’m a big fan of walking. But 5 miles to a grocery store and then back is going to be way too much and too dangerous for most people.

e-dant 3 hours ago||
It is an accomplishment in a healthy, pro-social environment.
calmbonsai 2 hours ago|||
But it's only a good judgment call if you have the available transit + shopping time, able body, suitable climate, and a single store that has everything you need.

If any of those conditions are not satisfied then it's better economic utility to outsource that entire task and get your exercise and socialization by going to the gym. You can even walk to the gym too. You can outsource almost anything except exercise.

oblio 54 minutes ago|||
It's still not practical. Humans just walk too slowly.

Let's be realistic here and accept the fact that anything that involves more than 1km of walking one way won't happen for 99% of people.

That's why we have bikes, for distances from 1km to 10-12km (one way).

And only after that should we have cars. Cars should also be reserved for very heavy loads (more than 50kg), groups of people (not single drivers, 2+ people in the car), and various other niche uses.

dzhiurgis 3 hours ago||
Nah just get an EV. Self driving one if you want extra piece of mind.