Posted by mustaphah 3 hours ago
Memory gain is noteworthy, which is the article's "wow" factor, but everyone's just knee-jerk smirking so ... here's a few random articles to gross you out about the wild world of trading microbiota and, for better or worse, changing your personality:
* "My butt made me crave candy."[1]
* "Gee, I'm not bipolar anymore thanks to my husband's butt juice infusion."[2]
[1] https://www.psychologytoday.com/us/blog/the-behavioral-microbiome/202404/hacking-an-individuals-personality-through-their-gut-contents
[2] https://www.abc.net.au/news/2025-07-28/faecal-microbiota-transplant-credited-with-curing-bipolar/105541522What's really cool is that the paper used low-dose capsaicin (just 5 μg/kg injected), and it completely restored hippocampal FOS activity and memory in older mice. Basically, that's the same stuff you get in cayenne pepper supplements - pretty easy to get your hands on.
[1] https://www.goodreads.com/book/show/28837738-the-mind-gut-co...
[2] https://www.goodreads.com/book/show/35210457-the-psychobioti...
Rather than jumping from one fad diet to another, just eat what you like and be sure to get a lot of fiber each day.
Sure sounds like another fad diet.
btw people, do drink water to keep up with the fiber. Otherwise it might not help.
"Why Isn't My Brain Working?"
by Datis Kharrazian
published in 2014 talked about this over a decade ago.
The connection between gut-brain has been studied in humans, as well as the effect of diet and gut bacteria on brain functions.
As far as I know, no such effect has been observed.
And this article claims inflamation from that strain, the NIH claims otherwise: "Parabacteroides goldsteinii is a next-generation probiotic gut bacterium with significant anti-inflammatory and metabolic benefits, often reduced in obese or diseased states. "
Edit: one of many examples: https://www.science.org/content/article/journal-retracts-inf...
I think for something this unexpected you'd want a much lower P.