Overview We are looking for a senior systems architect, not a feature developer. This role is for someone who: . has designed systems end-to-end . understands how to structure complex backend systems . can work alongside AI-assisted development (not against it) If your primary strength is writing features or following tickets, this is not the role.

What You Will Be Responsible For Evaluating existing systems and identifying what should be: kept, restructured, rebuilt Designing system architecture across: data flow, service boundaries, processing layers Structuring systems that involve: multiple data inputs (APIs, documents, etc.), document ingestion and parsing, asynchronous/background processing Defining backend patterns for: reliability, scalability, maintainability Working in an environment where AI tools (e.g. Claude, OpenAI Codex) are actively used for execution This is a design-first role, not a ticket-driven role.

How to Apply (Required) Please include: . A brief description of a system you personally designed end-to-end . The hardest architectural decision you made in that system . A short explanation of how you currently use AI tools in your workflow Applications without this information will not be considered.

Please email to Gpresearch2025@gmail.com

Due to the length of the comments, please visit this doc for full details: https://docs.google.com/document/d/1cCh3gjmq3QYrTKl4qv93QgD1...

We've already built a dental analytics tool to aggregate and analyze data across the dental industry. We now are looking to build AI Agents on top of our infrastructure to automate away the administrative tasks associated with running a small healthcare company.

We are looking for a A+ player to take charge on this effort. The infrastructure and network is there to sell to existing clients and scale fast.

Open Positions:

- Full Stack Engineer

- AI Engineer

No experience is required. I'm open to anyone who can demonstrate they are capable.

Pay will be equity, incentive, or salary based depending on your goals.

Email:

hiring@trydenta.com

Kredit (https://www.kredit.fyi) is on a mission to resolve consumer debt. We help people get out of financial hardship and offer tools for companies looking to manage their internal processes. Kredit is a small team and growing.

Our stack: .NET Core, C#, PostgreSQL, CQRS, Angular, GCP, Kubernetes, Terraform and much more. We are looking full-stack engineers that have a .NET background, eager to learn and motivated to work in a startup.

If this sounds interesting to you, please reach out to recruiting at trykredit.com

We're building an AI platform for molecular discovery: think language models for protein and DNA design. Small founding team, moving fast, real ownership.

Looking for a lead platform engineer to own full-stack development across our Console, Builder, and Solutions apps. You'll ship agentic workflows for molecular design, build integrations with sequence/assay ordering providers, and help shape the technical direction of the platform.

Stack: Python, React, Node.js, AWS, Docker, REST/WebSockets. Bonus if you have experience with agentic systems or MCP. Interest in biology/bioinformatics a plus but not required. If you've shipped production systems end-to-end, have strong product instincts, and want to work on something at the intersection of AI and life sciences - we'd love to hear from you.

https://app.dover.com/apply/BioLM/12435b30-67f1-43c2-8c59-6d...

We are building the next generation of infrastructure for AI without Docker containers, but with a better container technology based on WebAssembly!

We are hiring for:

  * Rust Engineer (Remote, EU timezone)
  * Rust Distributed Engineer (Remote, EU timezone)
  * Developer Education Engineer (Office, San Francisco)

We’re hiring for 3 roles Remote (UK/EU preferred):

1) Senior Product Designer Own UX/UI for the Aye Eye / Trojan app platform. Mobile/tablet journeys, wireframes, Figma design system, and clickable prototypes. First mission includes onboarding, dashboard, live view, alerts, device setup, AI query, shop, subscription, and settings.

2) Developer Platform Lead Define the self-serve developer ecosystem: portal structure, onboarding flows, documentation, sandbox model, and submission workflows.

3) Senior Full Stack Developer Build the portal behind that ecosystem: auth, dashboards, API keys, sandbox access, submission workflows, and licensing touchpoints.

We want people who can simplify complex systems, work fast, and ship clean, commercially usable product experiences.

Email: ayeeye.careers@gmail.com Subject: HN – [Role Name]

We’re looking for Python backend engineers to work on a trustless supercluster of performance-proofed GPU-enabled sandboxed docker container runners controlled by truly decentralized algorithms (not just PAXOS or RAFT).

Wow, that was a mouthful...

If you found it interesting, join Reef Technologies and tackle complex technical challenges like this on your own terms:

Contribute from wherever you like—we are fully remote Set your own time commitment, as long as it’s at least 30h per week See how we work in our handbook: github.com/reef-technologies/handbook Influence the way we operate through our Sociocracy 3.0 decision-making process

Salary on a B2B contract:

45-70 USD or 180-280 PLN per hour Flexible work schedule (as measured with a time tracker) We automatically adjust rates based on inflation twice a year

We're looking for someone with 5+ years of programming experience, including at least a year with Python (including opensource and significant personal projects).

So, what do you think? You don't even need a CV; just go to https://careers.reef.pl/?utm_source=hackernews and shoot a few quick commands to apply.

Contact: hiring@reef.pl Web: https://reef-technologies.com/

Tech stack: Rust | ScyllaDB | k8s | Python | Postgres | Elasticsearch | Terraform

Role: Build and operate distributed database systems and data platform services that store all of the data for Discord's 200M+ users.

We're solving interesting problems around performance, reliability, and scalability at one of the largest communication platforms. Looking for strong infrastructure and distributed systems experience, familiarity with databases like Cassandra/ScyllaDB/Postgres, and comfort working in Rust or similar systems languages.

https://discord.com/jobs/8200328002

We're building the Databricks for content production, starting with post. Our orchestration engine coordinates pipelines end to end and turns post-production workflows into a persistent graph of assets and transformations, which are deterministic, verifiable, and nearly instant at scale, powered by a high-performance compute layer. We're building this AI-native from the ground up; ML inference is embedded throughout the pipeline, not bolted on.

Stack: On-prem, HPC clusters, distributed storage systems, GPU pipelines, real-time video compute.

We're looking for our founding senior backend engineer who wants to work on genuinely challenging infrastructure problems across distributed systems and media processing with immense scale. Should be familiar with Golang, Postgres, Distributed systems, Distributed filesystems (e.g. HDFS, Ceph, etc). If that sounds interesting, reach out directly to me at wilson@postup.pro.

Me: https://www.linkedin.com/in/hayswilson/

How to apply: Email me directly at wilson@postup.pro or Submit here - https://www.notion.so/Founding-Senior-Backend-Engineer-31031...

Given the latest quantum algorithmic advances by Google, Bitcoin is expected to be fully broken by 2029. In this position you will design post-quantum cryptography that goes beyond the BIP-360 stopgap to fully solve the quantum threat on Bitcoin and transition it safely into the post quantum age.

Please describe your cryptographic experience, your Bitcoin experience and the flavor of PQ-crypto that you believe can save BTC. Apply to: savingbitcoin@pindush.net

(burner address for spam prevention, expect answers from a different email)