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Posted by defrost 9 hours ago

For first time, a cell built from scratch grows and divides(www.quantamagazine.org)
https://biotic.org/research/spudcell/
692 points | 238 commentspage 5
CurbStomper 8 hours ago|
[dead]
deadbabe 8 hours ago||
Going by people’s reactions to AI, what will our reactions be to artificial humans generated from these methods?

Will they be hated? Killed off? Will they ever be see as legitimate, or just soulless beings, p-zombies.

vhantz 7 hours ago|
From cells dividing to human generation there is a single step.

Similarly a program that runs on a computer, where its only interactions are strings of numbers is the same as an entity having to interact with the world.

deadbabe 7 hours ago||
Interesting, we should be able to have LLMs generate full genetic code or Inpaint into existing code that can be installed into a cell as DNA and have it divide out into any custom creature.

We could launch these custom bacteria in stasis to planets around the galaxy and seed life everywhere.

tete 3 hours ago||
You should be able. Go for it.
joh6nn 8 hours ago||
For the love of all things holy, can we not do these kinds of experiments on the same planet we live on?
JanJedryszek 4 hours ago||
:(
dyauspitr 8 hours ago|||
Oh shut up, can we get some frontier stuff going without some doom and gloom. All this knowledge for all these years and next to no progress.
snapcaster 8 hours ago||
I blame black mirror for this attitude. If you're going to speculate on imaginary futures why can't they be positive?
qsera 8 hours ago||
>why can't they be positive?

Because no one minds if good things happen...

germandiago 7 hours ago||
That is closer to consciousness than AI will ever be. :)
red75prime 7 hours ago||
Elan conscietal? (a pun on elan vital)
namero999 6 hours ago|||
Definitely. An implication of several strands of idealism is that we will be able to create artificial life (with consciousness)... it will just look like biology.
JanJedryszek 4 hours ago||
yes
blorbthrow 6 hours ago||
> 'Unlike living natural cells... the synthetic SpudCell can't survive and replicate without feeding on external food and ribosomes'

So in the future when there's a lab leak from the Wuhan Institute of SpudCellular Biology, the SpudCells will devour all biological life they can in order to harvest the building blocks they need. "Just social distance and wear two masks," the Surgeon General tells the CNN correspondent, as he disolves to red gray goo on live TV.

1-6 7 hours ago||
"The cell is not alive by any definition..." "But it’s the strongest demonstration yet that it is possible to generate life from nonlife."

Contradicting themself in the same paragraph.

tsunamifury 7 hours ago|
The wheel is not a car. However a wheel is a strong indication that car-like structures are at least possible.
commieneko 5 hours ago||
Interesting. I pasted the article URL into Claude Opus 4.8, along with some questions about uses for cells that couldn't reproduce and Claude thought about it for a while, and then got murdered by the guardrails. I was invited to edit the question and try again; in a different chat. Or use a dumber model.

I suppose I can see why. But at the time I was just curious about the idea of "mule" cells.

dist-epoch 4 hours ago||
Red blood cells can't reproduce and are "mule" cells - bags of hemoglobin. They are not really alive, so maybe not exactly what you were thinking of.
whycome 5 hours ago|||
What are the guardrails here?
commieneko 5 hours ago|||
I've read than even a lot of high school biology questions can set off safety guardrails on Claude.
bellowsgulch 5 hours ago|||
A lot of high school biology underpins the most immediate interesting aspects of chemistry and biology, and also the most volatile and dangerous ones.
libraryatnight 5 hours ago|||
I'm curious what you asked? I had Opus 4.8 ingest the URL and give me some ideas about what's possible and it eventually got to AI and self repairing/improving factories along with listing risks etc.
commieneko 5 hours ago||
Here's what I asked it:

"The idea of a cell that didn't reproduce at all occurred to me. Maybe created by a factory cell. It would be used to change an environment or produce some useful compound. I can imagine manufacturing them to process chemicals, or create mechanical structures. Put a network address in each one and they can be coordinated. The advantage of not reproducing is that they couldn't mutate if they had no reproduction mechanism at all. Can only come from the factory. Of course they could still be susceptible to viruses."

I've done a little googling since, and mule cells are actually a thing. In organisms they are very common. Neurons are an example. Parts of the immune system. There's also a thing in bacteria where cells divide, creating two daughter cells, one that can reproduce and one that can't. The one that can't makes a support structure around the one that can and then dies. This is how sporulation works.

None of this is deep, dark secret stuff. Some clumsy Wikipedia research got me this deep. If that's dangerous we are in deep sh*t.

(I'm not a biologist, I'm an animator who makes visualizations for university courses.)

IshKebab 5 hours ago|||
They're paranoid about people using AI to synthesise anthrax or something. You also can't ask it how to build a nuclear bomb.
bradley13 5 hours ago||
Which shows why guardrails on AI are just dumb. What harm could come from answering your question? None.
amai 6 hours ago|
The wikipedia website to "It's alive" (https://en.wikipedia.org/wiki/It's_Alive) lists mostly horror movies. So I'm not sure this is good news.