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Posted by RickJWagner 8 hours ago

Cannabis users face substantially higher risk of heart attack (2025)(www.acc.org)
144 points | 197 commentspage 3
khalic 6 hours ago|
Without a clear mechanism of action, this sure requires monitoring (like any drug), but the conclusions are terribly oversold. Correlation does not imply causation, no matter the sample size
jkuli 3 hours ago||
Is this really the largest factor they found in all our medical data?
jkuli 3 hours ago||
It's rare to see a study where "no link was found"
SV_BubbleTime 2 hours ago||
I love these articles. When the hundred heavy pot users all come at once with their impartial critiques and studious analyses.

What I like more is some of the people that will agree with me would crucify if the topic was about ADHD meds.

bsenftner 4 hours ago||
Come on people, it is a drug. Exercise, cardio, eat well, sleep well, it's your choice the risks you take, but try to balance the good with the bad, if you partake in "bad".
fuzzfactor 5 hours ago||
From what I've seen it's faced with a more stony resolve compared to side-effects of many USP substances.
yieldcrv 7 hours ago||
I’m annoyed by the bifurcated regulatory regime

Substances approved by the FDA are done based on specific treatments, with multiple trials and approval per use case

Substances declared scheduled are illegal by the substance itself, instead of per use case

paradoxically because there is no FDA approved use case and almost no way to get one

meaning that places in the US that diverge in legality and are ignored by the federal government have done so without any clinical trial, which would be some level of peer reviewed objective information by use case instead of the whole substance

we can’t even get a simple list of side effects, or a disclaimer about what kind of users shouldn’t use it

only anecdotes

that annoys me and it’s not just about weed

dofm 7 hours ago||
The US government is now in thrall to the Kratom industry though isn't it? No reason to expect any logical consistency from them.

(Literally the person currently responsible for the branch of government that keeps illegal drugs out of the country is an investor in a Kratom company)

steveBK123 7 hours ago||
Yes we are living in a kleptocracy / kakistocracy hybrid
slipperybeluga 7 hours ago||
The most ridiculous thing about cannabis remaining schedule 1 (high risk of abuse, no known medical use) so long is that there is both prescription THC and CBD. It should have been changed|to a higher (less strict) schedule decades ago with the release of marinol in 1985. Then we could have had a lot more studies being done. Needless to say, not easy to do studies on schedule 1 drugs.
yieldcrv 1 hour ago||
the two week hearing happening now mentioned marinol, with the DEA throwing its support behind that and rescheduling to schedule III, following the administration's policy aims (only mentioning because the head of DEA was anti-rescheduling before being appointed, spineless haha but I'm glad he's not in the way)
IAmGraydon 7 hours ago||
Literally no mention of ROA. It matters whether they smoke plant matter, vape, use it orally, etc. This, combined with their inability to account for a number of other factors such as tobacco use, makes this study literally useless. Earned a flag from me.
mil22 7 hours ago||
Agree on ROA, but the retrospective cohort study (one of two discussed in this article) did account for many other factors including tobacco use.
cynicalsecurity 5 hours ago||
Just a few years ago cannabis was presented online as a miracle drug that could cure all physical and psychological diseases. Any criticism of the sacred cannabis was strictly forbidden and dissenters were burned alive in the figurative fire of social media. Interesting how times are changing.
goodroot 5 hours ago||
I'm not so sure.

There's always been a pragmatic center on cannabis, especially if you're somewhere where it's legalized.

In Canada, we have legal cannabis.

https://www.canada.ca/en/health-canada/services/drugs-medica...

When it was legalized, there was a documentation push and clear presentation of the downsides. In fact, as above, the language is mostly presented in the negative.

This matches the general sentiment of the broad population.

And let's not conflate things. The article is discussing smoked cannabis. This does not invalidate the essential substance and benefit of the experience. If we remove the ingestion method from the basket of effects, it's a different discussion.

Not all positive, yet smoking is clearly not good for you.

Full stop, no matter what it is.

amanaplanacanal 4 hours ago|||
That was likely a reaction to the DARE/reefer madness propaganda many of us grew up with, which was obvious bullshit.
cj 5 hours ago||
See also: Bitcoin, Tesla/Musk, Apple
ck2 7 hours ago|
people just want their recreational drugs

it's as stupid as smoking/vaping and not even black box warnings will get people to stop

now if you need pain management I can respect that 100%

but you need to investigate Palmitoylethanolamide and Geraniol as alternatives

* https://news.ycombinator.com/item?id=48700498

balfirevic 5 hours ago||
> people just want their recreational drugs

Yes, people want to recreate, doing all kinds of activities with various levels of risk. They don't need to concern themselves with whether you can respect it.

block_dagger 6 hours ago||
Can you respect folks who are treating mental/emotional pain or just physical?
gedy 5 hours ago|||
The folks I know who attempt to 'treat' themselves with substances generally just get worse. That's not a judgement, just an observation.
switchbak 5 hours ago||
There are (illegal) substances that are highly effective for treating these issues, PTSD, etc. Psilocybin, ibogain, etc. Obviously when administered correctly, with therapy, etc.

It seems to me that cannabis users aren’t seeing the benefits of the aforementioned group. My experience of cannabis stoners is that it’s used to numb out and for escapism, which certainly aligns with what you’re saying.

ck2 6 hours ago|||
sure but you aren't going to help mental/emotional problems by getting stoned

there are far better, legal supplements to treat that anyway, less expensive too

dope activates AMPK in the brain/CNS and turns off AMPK in the body/heart it's an incredibly stupid thing to do to yourself (also why people get "the munchies")

literally why it's called dope (before dope meant "cool")

sscaryterry 5 hours ago|||
With enough tolerance, you don't get stoned anymore. This is where you want to be, side-effects gone, just the good stuff left.
galleywest200 5 hours ago|||
> less expensive too

Marijuana is dirt cheap compared to any prescription medication, at least in the US.

switchbak 5 hours ago||
They did say “legal supplements”, not prescriptions. But I’m not sure what they’re actually suggesting.
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