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Posted by aldarion 1/7/2026

Sugar industry influenced researchers and blamed fat for CVD (2016)(www.ucsf.edu)
797 points | 501 commentspage 2
rsync 1/7/2026|
One very minor side (art?) project I am doing:

https://kozubik.com/items/ThisisCandy/

… is a pushback of sorts on the sugar industry.

elektronika 1/7/2026|
If I were to design a warning label I would take inspiration from the Australian tobacco warning labels, quite gruesome medical imagery of rotted teeth. Restricting the form of advertisement would be a start, like USA tobacco regulations.
siliconc0w 1/7/2026||
This isn't really a correct narrative. Diets high in saturated fat are correlated with CVD. Sugar is also correlated with poor metabolic health which is also correlated with CVD. Both are bad.

Best data is still Mediterranean- nuts, fruits vegetables, olive or avocado oil, and lean protein.

tsimionescu 1/7/2026||
The so-called "Mediterranean diet" is a myth, and one of many myths that even serious "nutrition scientists" believe and perpetuate. Actual people in the Mediterranean have way different diets, and ones that include significant quantities of things like pork, lamb, fatty fish, very sugary confections, processed meats like sausages or jamon, etc.

I would be willing to bet that things like the siesta, large amounts of sunlight exposure, a more laid back culture, and lots of vacation days are much more important parts of what keeps people living around the Mediterranean healthier - much more so than the actual diet.

aldarion 1/7/2026|||
Mediterranean diet is basically a lie, though. If you look at the healthiest Mediterranean populations, they eat a lot of saturated fat.

Diets high in saturated fat are correlated with high standard of living. High standard of living is correlated with high consumption of processed foods. So... yeah.

Panoramix 1/7/2026|||
I've been to the Mediterranean several times. They eat a ton of (delicious) super oily food, sausages, meats, eggs, fish (often fried or deep fried), salty cheeses, greasy stuff, tons of white bread, lots of wine. Fat chance to find someone eating avocados, kale, or quinoa, and proteins are not at all minimized.

The Mediterranean diet is like a Californian wellness type of person's idea of what the actual Mediterranean diet is.

tonyedgecombe 1/8/2026||
Countries in the mediterranean have been developing the same bad habits as elsewhere. People in the Mediterranean need to go back to eating a Mediterranean diet.
nephihaha 1/7/2026|||
Fruit and veg can be contaminated with sprays as well unfortunately.

The vegetarian aisle used to be healthier but now it's been invaded by ultraprocessed food too.

I find a meat heavy diet works with keeping weight off. The opposite of what we've been told.

astura 1/7/2026||
Sprays?
nephihaha 1/7/2026||
Fertiliser, insecticide, herbicide (for controlling certain weeds etc)...
D-Machine 1/8/2026||
Mediterranean diet is nonsense. Ill-defined, doesn't have clear evidence of a relation to CVD in hard studies. Bad that people still believe this.

https://pmc.ncbi.nlm.nih.gov/articles/PMC6414510/

lfliosdjf 1/7/2026||
Has any one successfully code with same focus after cutting sugar? Seems sugar is really important for focus. Whats your experience?
lowbloodsugar 1/8/2026||
If you're addicted to cocaine, then cocaine is really important for focus. Same for sugar. If sugar is really important for focus for you, then you're likely heading for diabetes type 2.
anthomtb 1/7/2026|||
I did keto for a few months a long time ago (2010/2011). This was early in my career and long coding and debug sessions were a normal part of my day-to-day.

There was zero impact to my work focus, positive or negative, from cutting nearly all carbohydrates out for several months.

I am curious were you heard or learned that "sugar is really important for focus". Just a vibe, perhaps?

lfliosdjf 1/7/2026||
Personal experience. Then I found many well known programmers shared the same experience online. It feels deliberate work without sugar. ie. if coding = work + fun. without sugar its just coding = work. It does not get any better after 3 days or so too.
GloamingNiblets 1/7/2026||
It might feel good but spiking your blood sugar isn't healthy for you, and the crashes afterwards will get worse over the years. Improving metabolic health might be a better long term solution; have you explored how endurance or high intensity exercise affects your focus?
united8932 1/7/2026|||
Been coding while fasting on keto and it's absolutely amazing. Fasting is hard socially, being ketogenic puts a bit more stress on my kidneys, but for me (adhd) it's amazing.

remember your brain can run on ketones which provides a more stable energy than glucose spikes. the brain is metabolically flexible, can run on glucose, ketones or lactate

331c8c71 1/7/2026|||
If anything focus gets better without sugar and excessive carbs for me - but those work well for outdoors or workouty days I find.
mixmastamyk 1/8/2026||
Definitely, carbs means alternating drowsy, hunger cycles with blood sugar level. While an even level enables the zone.
CrimsonRain 1/8/2026|||
That's addiction. You'll need time to get out of it.

Cutting off sugar will help you have more focus, not just during coding but the whole day. However, if you were on high amount of sugar before, at initial stage, your body will scream.

For me, it takes a few weeks to get settled in. After that, I don't miss sugar at all. Can focus just fine.

aldarion 1/8/2026|||
I don't code, but I do know that not eating sugar significantly improves my focus no matter what I'm doing.
shimman 1/8/2026|||
I have never heard of anyone using sugar to "focus," if you want to focus take amphetamines or cocaine.
NoPicklez 1/8/2026||
Why are you cutting out sugar, unless you mean reduce. But you shouldn't stop eating sugar, its required, just not in excessive amounts.
fercircularbuf 1/8/2026||
Not required to eat any sugar at all. Your body will actually produce its own glucose if and when needed through gluconeogenesis [1].

[1] https://en.wikipedia.org/wiki/Gluconeogenesis

NoPicklez 1/8/2026||
Yes it can and it does that when there is an absence of available glycogen provided through carbohydrates, it is not to replace but to support in addition to appropriate sugar intake. It is a less efficient source of glucose, does not provide a large enough amount for exercise and also uses amino acids from muscle to help. Do this long enough and you end up in ketosis which is a whole other kettle of fish.

Why neglect one aspect of our bodies digestive energy systems for just gluconeogenesis. Wouldn't you be better off eating a balanced meal of complex carbohydrates and unsaturated fats. Our bodies have multiple pathways to producing energy, focusing on using only one is silly and not the right approach because it wasn't designed to be that way.

Just because our bodies can survive doing a particular thing in the absence of another, doesn't mean that thing we're absent of isn't required.

lfliosdjf 1/8/2026||
Its optimal to solve all the constraints or requirements of needs of the body. But we don't fully understand the requirements as a whole and conflicting information from expertsh. So the rational thing is to rely on the historical data and make judgements on the probability.
StopDisinfo910 1/7/2026||
A casual look at where people live the oldest, what they eat, and what's recommended tell you all you need to know about food recommendations then and now.

It's a field where actual long term controlled experiments are impossible, confounding variables are everywhere, and multiple lobbies have vested interests in the outcomes.

I take everything with a grain of salt apart from studies of harm when sources are credible and numerous and even then, I'm not fully confident.

The only current advice I follow is avoiding industrially processed food. That sounds like a sound one as this kind of food is basically terra incognita. It's just applying the precaution principle.

stavros 1/7/2026||
A casual look at where people live the oldest will tell you about statistical outliers and bad government recordkeeping.
Aloisius 1/7/2026||
Don't forget pension fraud and identity theft.
lithocarpus 1/7/2026|||
I think avoiding industrially processed food is wise, but it eliminates 99% of restaurant food and 90% of prepared food in almost any setting, only exception being about half the stuff at a salad bar.

Almost everything that isn't a single ingredient whole plant or animal food contains industrially processed oil or sweetener/starch.

Still worth doing imho but I understand why it's not easy for most people.

StopDisinfo910 1/8/2026||
It doesn't have to be a religion. I don't care when I eat out. The point is not to be absolutely consistant. It's just the guideline I use regarding what I eat.

I don't really eat prepared food. I mostly buy whole food to be used as ingredients. Cooking simple meals is not particularly hard. I think most people overestimate the complexity and time requirement involved.

Maxion 1/7/2026|||
> The only current advice I follow is avoiding industrially processed food.

It is also surprisingly hard in practice. There are so many foods that on the label are supposed to be whole foods or low processed but then when you read the ingredients do you realize you've been bamboozeld.

m4rc3lv 1/7/2026||
For me avoiding processed foods is not that hard, I only eat whole foods like vegetables and fruits (where I live there are no labels on these whole foods). I know that this is not doable for most of you, but it can be done if you want. https://en.wikipedia.org/wiki/Plant-based_diet
llmslave 1/7/2026||
This is a complete myth. Human populations are not homogenous, gene pools that relied on agriculture for the last 10k years are completely different than hunter gatherer populations. You have been lied to
StopDisinfo910 1/8/2026|||
Which myth? I have genuine trouble understanding what you disagree with.

Industrially processed food is a very recent invention. I'm not talking about modern fad like the Nova classification here. I don't care about bread as long as it's made with water, yeast and flour. I just don't want my food to contain any recent additives.

My take is basically that if it was fine a thousand years ago, it's probably ok-ish minus everything we know now to be poisonous. The blind spot is obviously plant selection and modern varieties being different but well, that's ok, nothing is perfect.

boilerupnc 1/7/2026||||
The diversity in individual micro-biome ecosystems now walks into the room
NoPicklez 1/8/2026||
Doesn't both sugar and saturated fat contribute to CVD if consumed in excess?
pcblues 1/8/2026||
Not sure if this has been posted (I see stephenwoo has mentioned him further down), but it's a break-down of how sugary foods damage the body, particularly fructose.

It's 16 years old about 30 years of previous research.

https://www.youtube.com/watch?v=dBnniua6-oM

ChrisArchitect 1/7/2026||
Related (reason why OP submitted this today?):

Eat Real Food – Introducing the New Pyramid

https://news.ycombinator.com/item?id=46529237

ChrisArchitect 1/7/2026||
(2016)

Some other discussions:

2024 https://news.ycombinator.com/item?id=41962750

2022 https://news.ycombinator.com/item?id=32978590

2021 https://news.ycombinator.com/item?id=26126183

and on and on...

2016 https://news.ycombinator.com/item?id=12480733

jqpabc123 1/7/2026||
Which will make you fatter?

    A) Eating a pound/kg of fat

    B) Eating a pound/kg of refined sugar
Correct answer: B

Sugar enters your blood stream almost immediately --- starting in your mouth. Unless you're doing heavy exercise and burning lots of calories, your body has to store most of this excess energy --- as fat.

The only way to get consumed fat into your bloodstream is to first convert it into sugar --- which itself burns some energy.

timerol 1/7/2026||
Note that a kg of fat contains about 9000 calories, while a kg of sugar contains about 4000 calories, so this is really a startling claim, if true
brodouevencode 1/7/2026|||
It's not given the ratios

OP should have said for calorie-adjusted intake sugar is more fattening.

jqpabc123 1/9/2026|||
It is about more than just the calorie content of the food.

Unless your digestive system is hyperactive, a lot of this huge glob of fat will likely just pass right through without being absorbed into your bloodstrean.

The refined sugar is virtually guaranteed to fully hit your bloodstream and right now. It's enough to send some people into a life threatening diabetic coma.

After eating a pound of fat, you may want a nap but dying from it is extremely unlikely.

cyberax 1/7/2026|||
> The only way to get consumed fat into your bloodstream is to first convert it into sugar --- which itself burns some energy.

Fat does not get converted into glucose in normal conditions in appreciable quantities. It's used as-is, most of the body can directly utilize fatty acids as a fuel source.

Also, body has a lot of mechanisms to deal with sugar. It is normally stored in the liver and then released slowly.

brodouevencode 1/7/2026|||
But it will always prefer glucose stores over fat.
hinkley 1/7/2026|||
And the muscles. You can’t fight or flight if you have to ask the liver to deliver glycogen. That’s how anaerobic exercise works. You have the fuel but not enough oxygen to burn it so you burn it fuel rich and oxidizer poor.
BirAdam 1/7/2026||
Not quite. The body will just enter ketosis if glucose and glycogen levels are too low.
cyberax 1/8/2026||
The grandparent means something a bit different. Muscles can use glucose without _oxygen_ to get short bursts of energy quickly by rearranging glucose molecules (indirectly) into lactic acid.

Ketones can't be used for this purpose.

hinkley 1/8/2026||
Glycogen is stored in the muscles and in the liver, not just the liver. The liver holds around half of your reserves.
jimmar 1/7/2026|||
https://pubmed.ncbi.nlm.nih.gov/7598063/

> Carbohydrate overfeeding produced progressive increases in carbohydrate oxidation and total energy expenditure resulting in 75-85% of excess energy being stored. Alternatively, fat overfeeding had minimal effects on fat oxidation and total energy expenditure, leading to storage of 90-95% of excess energy.

Also, it's just not true that consumed fat must be turned into sugar before entering the bloodstream. See https://med.libretexts.org/Courses/American_Public_Universit...

NoPicklez 1/8/2026|||
There's more nuance to this.

Yes sugar enters your blood stream almost immediately which isn't a bad thing, but not all of it. A large amount of that sugar gets stored in the liver as glycogen and any of that not used becomes body fat.

But also

Yes when you consume fat, it is converted to be used by the body as energy however the excess of that similar to sugar is also converted into body fat.

Importantly, 1kg of fats and carbs have wildy different energy levels with 1kg of fat representing 7,700 calories and 1kg of carbs being around 4,000 calories. So yes it burns energy to convert fat into energy, but you have a lot more energy to burn for the same amount eaten.

This is why carbs and fats have different recommended daily intake levels. Therefore, most of what causes CVD is actually due to overconsumption rather than a balanced meal that doesn't take you into constant excess of either carbs or fats.

tsimionescu 1/7/2026||
At the same weight, fat contains way more calories than sugar, so the difference in difficulty of digestion is irrelevant at this level. It's true that if you were to consume 1000 Cal worth of sugar vs 1000 Cal worth of fat, you'd get slightly less fat from the fat - but this should be seen simply as one of many limitations on the "calories in" measurement. The same kinds of differences likely exist between different sugars, different fats, different proteins - and may well be affected by other aspects of how the food containing these nutrients is consumed; and it almost certainly varies a lot between people or even for the same person based on various factors such as age, activity level, time of day, etc.
bell-cot 1/7/2026|
Maybe I read too much history - but hasn't Big Sugar been known for "nothing that a slave trader wouldn't do" ethics for the past 300+ years?
qsera 1/7/2026||
It is beyond me how anyone can expect any business (especially public traded) to have any ethics whatsoever.
Balinares 1/7/2026|||
In strong democracies, regulations provide the incentive.
qsera 1/7/2026||
..and you think those work?
admash 1/7/2026|||
Of course they do, if enforced. The number of eight year-olds working in factories is substantially lower than it used to be due to regulations. *in modern democracies
qsera 1/8/2026||
>if enforced..

There lies the problem...

https://news.ycombinator.com/item?id=46528718

jethro_tell 1/7/2026|||
If you do regulate. We currently have full regulatory capture in most industries and regulators that are doing their jobs are either hamstrung or the laws are so far behind the industries that they can’t or won’t work.

The key to proper regulation is to keep money and influence from pooling at the top, making it difficult for any single person to buy enough influence.

As it is, we have a dozen monopolies that should be broken up that are making a small section of the population so rich they are essentially above laws.

But, proper regulation can exist if people want it, and more specifically in the case of the USA, legislators want it. Unfortunately, Dems actively prevent it, and republicans are ripping it down, so the rest of us are kinda fucked.

qsera 1/7/2026||
Regulations can work if bypassing the regulation in question does not open up a market that is large enough to keep paying off the regulators.

For example, if there is only one regulator for a country, the companies can pay millions to get it eased up for them, because they can make billions from it.

But if there one regulator for each state, they equation will change and it might not be profitable to pay millions to a regulator of the state, because they cannot make enough profit from selling in the state to justify it.

That is the only way to make it work. Rules don't work forever. Incentives do.

hinkley 1/7/2026||||
We literally had a circular slave trade of slaves->sugar cane->rum->slaves
jacobthesnakob 1/7/2026|||
They’re out there. I find it more productive to search for and financially support such businesses, rather than adopt the doomer pessimistic anticapitalism take.

For example I just bought a Concept2 RowErg rowing machine. They sell literally every piece and part on their website so it’s end user repairable. The metrics integrate with a ton of apps, so you’re not locked into their app/ecosystem and there’s no subscription. It’s the polar opposite of Peloton and Hydrox.

Unfortunately a lot of these honest businesses are one generation away from potentially selling out everything the founders built, but I’ll continue doing my best to keep them around while they exist.

qsera 1/7/2026||
>I find it more productive to search for and financially support such businesses, rather than adopt the doomer pessimistic anticapitalism take...

But sadly, many order of magnitude more people would like to just make more money when invest. Which is why..

>Unfortunately a lot of these honest businesses are one generation away from potentially selling out everything the founders built,

> rather than adopt the doomer pessimistic anticapitalism take...

Capitalism does not imply public trading. Capitalism can work even when companies re-invest parts of their profits.

Oh no, that would be too slow. We want Speeeed...even if that means a quick descent into certain doom.

jacobthesnakob 1/7/2026||
>many order of magnitude more people would like to just make more money when invest

Blame them (the consumers) then. This is like that silly Reddit/Twitter stat about 10% of companies creating 90% of global emissions… which the companies are doing in the process of making the shiny cell phones and laptops all the consumerists lambasting them are posting from, plus all the plastic crap they buy every day from Amazon.

The consumers are the ones demanding unchecked expansion of their consumption. As long as that demand exists, companies will find a way to fill it, whether they’re doing so in America or other countries. Privately held entities can’t allocate capital fast enough to keep up with the consumerists.

qsera 1/7/2026||
cant blame the consumers who are brainwashed by the ads that uses every weakness in human nature to create phantom needs, making up artificial demand for things..
lostlogin 1/10/2026||
Most countries ban direct to consumer drug advertising.

America is one of few places that doesn’t.

umanwizard 1/7/2026|||
Well, it's true that in the 17th century, sugar and rum production involved one of the most heinous forms of slavery ever to exist. What's not clear is that this necessarily has anything to do with the present; after all, slaves were emancipated a long time ago.

I think this is an instance of "large corporations in the 20th and 21st century have been intrinsically amoral" rather than "the sugar industry is intrinsically particularly evil (and has been since the 1600s)".

vintermann 1/7/2026||
Sure, but do you trust Big Butcher?
Avshalom 1/7/2026|||
And of course big sugar is these days just big corn which is happy selling to CAFOs.
rhyperior 1/7/2026||||
Not when so much meat has sugar added to it.
goalieca 1/7/2026||
Sugar makes an excellent spice, not a primary ingredient. It's really useful for grilling for instance.
bell-cot 1/7/2026|||
Based on the history of the past 1-ish century, I trust Big Meat & Dairy to have less capability for and competence at evil than Big Sugar. Because otherwise we'd have been hearing far more "Fat is Fine, Carbs are Crap" messages.
triceratops 1/7/2026|||
> I trust Big Meat & Dairy to have less capability for and competence at evil

Why? You've never heard of https://en.wikipedia.org/wiki/Ag-gag?

wang_li 1/7/2026||||
Well, there are essential amino acids and essential fatty acids, but no essential carbs.
zdragnar 1/7/2026||||
Well, there's the whole atkins and keto fads...
Avshalom 1/7/2026||
And Atkins really started picking up in the 90s which was

https://web.archive.org/web/20120629041358/http://www.ers.us...

Oh hey right after beef CAFOs started dominating the industry.

DetectDefect 1/7/2026||||
Surely you jest as the animal agriculture industry is many times larger than any "big sugar" boogeyman.
bell-cot 1/7/2026||
"Bigger = Badder" is quick & easy heuristic, but not a particularly accurate one.
DetectDefect 1/7/2026||
It is when it comes to slaughtering 80 billion sentient animals each year.
vintermann 1/7/2026|||
I feel like I hear that a lot.
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