I feel like this article leaves out the latest research pointing to acetaminophen having a negative effect on fertility, hindering embrionic development and potentially also also follicular development in baby girls. It's a trade-off for sure, but if you're trying to have a baby, you may want to swing back to ibuprofen.

[1] https://pubmed.ncbi.nlm.nih.gov/40819833/

[2] https://ddeacademy.dk/ddea/what-new-research-reveals-about-p...

If acetaminophen was invented today it would almost certainly be available by prescription only because of the safety concerns. There are far more benign medications that are Rx only.

You can combine the two for better effect.

1g of Paracetamol with 400mg of Ibuprofen gives similar pain relief as 2mg of IV morphine.[1]

[1] https://pubmed.ncbi.nlm.nih.gov/29017585/

> You should not switch medications based on the uninformed ramblings of [crazy] people.

Well, I mean, drats. I too always assumed Ibuprofen was safer than Acetaminophen; not the least because of massively oversimplificatic "reduced inflammation - GOOD!" 'Logic'. I'm 47 now and have probably preferred ibuprofen for last 27 or so.

After reading this, I wonder whether maybe low doses of morphine over a short period are safer than either.

If you have serious pain, you probably need both of them.

This is a repost from an article that was posted last week: https://news.ycombinator.com/item?id=47799088