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Posted by jader201 13 hours ago

Taxi drivers rarely die of Alzheimer's(theconversation.com)
216 points | 162 commentspage 2
panabee 2 hours ago|
The overall dataset was very large (8,972,221 deaths), but only 1,348 ambulance drivers were included, and just 10 had Alzheimer’s disease as the underlying cause of death.

Such a small number of outcomes matter because statistical precision depends on the number of relevant events. With only 10 Alzheimer’s deaths, even a small change in the count could substantially alter the estimated association.

Taxi drivers provided more robust data, with 171 Alzheimer’s deaths among 16,658 decedents, but death-certificate Alzheimer’s mortality may not reflect how often taxi drivers develop the disease. Differences in diagnosis or cause-of-death reporting across occupations could influence the observed association.

The large overall sample does not eliminate uncertainty in the much smaller occupational subgroups, particularly among ambulance drivers.

Nonetheless, this is an interesting study and merits further investigation.

Melatonic 6 hours ago||
One of the first things to go with Alzheimer's is spacial mapping in the brain so this makes sense. Your exercising daily a part of the brain that is involved.

In addition there's the social component of driving - you may not always want to talk to a Taxi driver but many people do. And ambulance drivers are often socializing with their colleagues

Driving also has a mix of reaction time based skills and hand eye and hand foot coordination. Overall it's pretty complicated.

Writing this I'm realising the final "Turing" test for AI might actually be just replacing the average Taxi driver. Can it drive a car, choose a route dynamically based on day and traffic and weather, and have a conversation with a wide variety of people and topics all at the same time ?

pmxi 2 hours ago|
This test would be passed by a Waymo with ChatGPT.
swrrt 3 hours ago||
Taxi drivers in old days needs to remember the whole map of their city, I think that is an efficient exercising/training that recommended for anti-Alzheimer, just like playing puzzles or quiz for oldman? But nowadays it is all about google map, not so sure about the effectiveness.
swang 2 hours ago||
Wasn't there some an article/video from somewhere where a man had worked in a hot environment (I think it was on a navy ship in the engine room) and even though his family had a history of Alzheimer's, he never showed any signs of it. Does anyone know what I'm talking about? (Might not be Alzheimer, might be thinking of another disease)
yfontana 8 hours ago||
Something interesting that the original study looked at, but isn't mentioned in the linked article: this effect was not observed for non-Alzheimer's dementia deaths. There seems to be something specific to spatial reasoning and Alzheimer's.
pama 6 hours ago|
Alzheimers has a very long development stage compared to almost all other dementia (Lewis body also has a long timeline, but none of the other forms has anywhere close to the known length for Alzheimer’s disease). The original study article has no causal analysis, so a simple explanation is that super early Alzheimers symptoms (possibly even undetectable ones outside the context of intense taxi driving) drives people to abandon their taxi- or ambulance-driving jobs and seek other forms of employment.
akamaka 5 hours ago||
I wonder if alcohol consumption plays a role here, since it is a known risk factor for Alzheimer’s. A taxi driver who works 60 hours a week will have very little time left over for drinking, whereas pilots have relatively short work hours where they actually need to be sober.
jere 3 hours ago|
> A taxi driver who works 60 hours a week will have very little time left over for drinking

That's plenty of time to be a full blown alcoholic.

akamaka 1 hour ago|||
You don’t need to be a full blown acoholic to be affected, it’s simply a correlation of more alcohol consumption to faster decline of the brain. Having a job that requires you to be sober more hours of the week might bump you into a lower risk category.
lazyasciiart 2 hours ago|||
Not to mention that your full time alcoholic isn’t taking 12 hour shifts off to be sober.
Havoc 12 hours ago||
Seems strange to me that a specific type of thinking could influence something where most causes being investigated are physical
teeray 11 hours ago||
Unless the arrow of causality is the other way: those that would tend to develop memory problems do not become or remain as Taxi drivers.
jvanderbot 11 hours ago||
Right, so we're speedrunning the studies here. Best to just stopover on TFA and see what they found.

For example, airline pilots do not have a reduced level of alzheimers deaths, and that _certainly_ is not a place where you can coast with dementia.

And taxi drivers have _increasing_ anti-Alzheimer signals - with time, the areas that are known to diminish grow _more_.

jkahrs595 12 hours ago|||
Not strange when you realize thinking is also physical.
cesarvarela 11 hours ago|||
Wouldn’t thinking be like exercise for the mind? And we know what happens to people that don’t exercise
toomuchtodo 12 hours ago||
Perhaps specific types of thinking cause somewhat sustained brain activity during waking hours that mitigates adverse physical changes leading to Alzheimer’s.

The opposite of this is how sleep and unconsciousness allows the brain to perform cerebrospinal fluid transfer based maintenance routines via the glymphatic system, and why sleep is important to neural health.

https://www.science.org/content/article/scientists-uncover-h...

al_borland 12 hours ago||
My grandfather was a taxi driver and delivery driver for many years. He made it to 93 and I don't recall him dealing with any cognitive decline. He used to tell me different routes to get to a stadium that was closed before I was even born.
id 10 hours ago|
n=1
layer8 9 hours ago||
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Perenti 2 hours ago||
How many elderly Taxi drivers die of traffic accident? Perhaps the job is culling the Alzheimer's sufferers before other symptoms and signs arise?
lambdaone 7 hours ago|
I wonder if the same is also true of other high-spatial-complexity activities like rock climbing and professional dancing? (Exercise level would of course be a counfounding varable to be eliminated in these cases.)
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